Andrea Brand Lab

Website for Andrea Brand Lab at the Gurdon Institute, University of Cambridge

Publications

Please contact Andrea if you would like to request reagents from our publications.

Most recent articles

Featured

Quiescent neural stem cells transiently become 'neurons' to coordinate reactivation

Gherghina L-Y, Tang J, Brand, AH

biorxiv

Quiescent neural stem cells transiently become 'neurons' to coordinate reactivation

Gherghina L-Y, Tang J, Brand, AH

biorxiv

2024

Gherghina L-Y, Tang J, Brand, AH

biorxiv

Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal dementia neurons and extends lifespan in an in vivo Drosophila tauopathy model

Paonessa, F, Delarue Bizzini B, Campbell T, Solanki R, Butler, R, Smith, J, Davidson, CM, Laurrieu D, Brand AH, Livesey FJ

biorxiv

Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal dementia neurons and extends lifespan in an in vivo Drosophila tauopathy model

Paonessa, F, Delarue Bizzini B, Campbell T, Solanki R, Butler, R, Smith, J, Davidson, CM, Laurrieu D, Brand AH, Livesey FJ

biorxiv

2024

Paonessa, F, Delarue Bizzini B, Campbell T, Solanki R, Butler, R, Smith, J, Davidson, CM, Laurrieu D, Brand AH, Livesey FJ

biorxiv

Targeted DamID detects cell-type specific histone modifications in vivo

van den Ameele, J., Trauner, M., Hörmanseder, E., Donovan, A. P. A., Llora-Battle, O., Cheetham, S.W., Krautz, R., Yakob, R., Gurdon, J. B., Brand, A. H.

biorxiv

Targeted DamID detects cell-type specific histone modifications in vivo

van den Ameele, J., Trauner, M., Hörmanseder, E., Donovan, A. P. A., Llora-Battle, O., Cheetham, S.W., Krautz, R., Yakob, R., Gurdon, J. B., Brand, A. H.

biorxiv

2024

van den Ameele, J., Trauner, M., Hörmanseder, E., Donovan, A. P. A., Llora-Battle, O., Cheetham, S.W., Krautz, R., Yakob, R., Gurdon, J. B., Brand, A. H.

biorxiv

Quiescent neural stem cells transiently become 'neurons' to coordinate reactivation

2024

Gherghina L-Y, Tang J, Brand, AHNovember 21, 2024biorxiv

Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal dementia neurons and extends lifespan in an in vivo Drosophila tauopathy model

2024

Paonessa, F, Delarue Bizzini B, Campbell T, Solanki R, Butler, R, Smith, J, Davidson, CM, Laurrieu D, Brand AH, Livesey FJNovember 21, 2024biorxiv

Targeted DamID detects cell-type specific histone modifications in vivo

2024

van den Ameele, J., Trauner, M., Hörmanseder, E., Donovan, A. P. A., Llora-Battle, O., Cheetham, S.W., Krautz, R., Yakob, R., Gurdon, J. B., Brand, A. H.November 21, 2024biorxiv

Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease

2023

Lim K, APA Donovan, Tang W, Sun D, He P, Pett JP, Teichmann SA, Marioni JC, Meyer KB, Brand AH, Rawlins ELFebruary 28, 2023Cell Stem Cell

In vivo, genome-wide profiling of endogenously tagged chromatin-binding proteins with spatial and temporal resolution using NanoDam in Drosophila

2022

Tang JLY, Krautz R, Llorà-Batlle O, Hakes AE, Fox PM, Brand AHJanuary 27, 2023STAR Protocols

SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling

2022

Sun D, Llora-Batlle O, van den Ameele J, Thomas JC, He P, Lim K, Tang W, Xu C, Meyer KB, Teichmann SA, Marioni JC, Jackson SP, Brand AH, Rawlins ELSeptember 23, 2022The EMBO Journal

The Drosophila homologue of CTIP1 (Bcl11a) and CTIP2 (Bcl11b) regulates neural stem cell temporal patterning

2022

Fox PM, Tang JLY, Brand AHSeptember 20, 2022Development

NanoDam identifies Homeobrain (ARX) and Scarecrow (NKX2.1) as conserved temporal factors in the Drosophila central brain and visual system

2022

Tang JLY, Hakes AE, Krautz R, Suzuki T, Contreras EG, Fox PM, Brand AHMay 31, 2022Developmental Cell

Reduced chromatin accessibility correlates with resistance to Notch activation

2022

van den Ameele J, Krautz R, Cheetham SW, Donovan APA, Llorà-Batlle O, Yakob R, Brand AHApril 25, 2022Nature Communications

Escargot controls somatic stem cell maintenance through the attenuation of the insulin receptor pathway in Drosophila

2021

Sênos Demarco R, Stack BJ., Tang AM, Voog J, Sandall SL, Southall TD, Brand AH, Jones DLApril 22, 2022Cell Reports

In vivo targeted DamID identifies CHD8 genomic targets in fetal mouse brain

2021

Wade AA, van den Ameele J, Cheetham SW, Yakob R, Brand AH, Nord ASJanuary 24, 2022

Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila

2021

News coverage: EurekAlert!, MedicalResearch.com

Agrawal N, Lawler K, Davidson CM, Keogh JM, Legg R, INTERVAL, Barroso I, Farooqi IS , Brand AHNovember 25, 2021PLOS Biology

The Serine Protease Homolog, Scarface, Is Sensitive to Nutrient Availability and Modulates the Development of the Drosophila Blood–Brain Barrier

2021

Contreras EG, Glavic A, Brand AH, Sierralta JAAugust 24, 2021The Journal of Neuroscience

Stem cell niche organization in the Drosophila ovary requires the ECM component Perlecan

2021

Díaz-Torres A, Rosales-Nieves AE, Pearson JR, Mateos C S-C, Marín-Menguiano M, Marshall OJ, Brand AH, González-Reyes AApril 13, 2021Current Biology

Mapping RNA-chromatin interactions in vivo with RNA-DamID.

2020

Cheetham SW and Brand AHApril 9, 2021Methods in Molecular Biology

Tailless/TLX reverts intermediate neural progenitors to stem cells driving tumourigenesis via repression of asense/ASCL1

2020

Hakes AE and Brand AHMarch 6, 2020eLife

Quiescent Neural Stem Cells for Brain Repair and Regeneration: Lessons from Model Systems

2020

Otsuki L and Brand AHMarch 4, 2020Trends in Neurosciences

Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration

2019

Aloia L, McKie MA, Vernaz G, Cordero-Espinoza L, Aleksieva N, van den Ameele J, Antonica F, Font-Cunill B, Raven A, Cigliano R A, Belenguer G, Mort RL, Brand AH, Zernicka-Goetz M, Forbes SJ, Miska EA and Huch MNovember 4, 2019Nature Cell Biology

Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation

2019

van den Ameele J and Brand AHSeptember 27, 2019eLife

Neural stem cell dynamics: the development of brain tumours

2019

Hakes AE and Brand AHJuly 19, 2019Current Opinion in Cell Biology