Recent Publications

Full Publication List

Featured
Christensen JB, Donovan APA, Moradi M, Vanacore G, Helmy M, Reid AJ, Lee JTH, Bayraktar OA, Brand AH, Bayin NS.
Development
A conserved differentiation programme facilitates inhibitory neuron production in the developing mouse and human cerebellum.
Christensen JB, Donovan APA, Moradi M, Vanacore G, Helmy M, Reid AJ, Lee JTH, Bayraktar OA, Brand AH, Bayin NS.
Development

2025

Christensen JB, Donovan APA, Moradi M, Vanacore G, Helmy M, Reid AJ, Lee JTH, Bayraktar OA, Brand AH, Bayin NS.
Development
Malkowska, A., Ander, J., Brand, A. H.
biorxiv
Neural stem cell quiescence is actively maintained by the epigenome
Malkowska, A., Ander, J., Brand, A. H.
biorxiv

2025

Malkowska, A., Ander, J., Brand, A. H.
biorxiv
van den Ameele, J., Trauner, M., Hörmanseder, E., Donovan, A. P. A., Llorà-Batlle, O., Cheetham, S. W., Krautz, R., Yakob, R., Malkowska, A., Gurdon, J. B., Brand, A. H.
PLOS Biology
Targeted DamID detects cell-type-specific histone modifications in intact tissues or organisms
van den Ameele, J., Trauner, M., Hörmanseder, E., Donovan, A. P. A., Llorà-Batlle, O., Cheetham, S. W., Krautz, R., Yakob, R., Malkowska, A., Gurdon, J. B., Brand, A. H.
PLOS Biology

2025

van den Ameele, J., Trauner, M., Hörmanseder, E., Donovan, A. P. A., Llorà-Batlle, O., Cheetham, S. W., Krautz, R., Yakob, R., Malkowska, A., Gurdon, J. B., Brand, A. H.
PLOS Biology
Gherghina L-Y, Tang J, Brand, AH
biorxiv
Quiescent neural stem cells transiently become 'neurons' to coordinate reactivation
Gherghina L-Y, Tang J, Brand, AH
biorxiv

2024

Gherghina L-Y, Tang J, Brand, AH
biorxiv
Paonessa, F, Delarue Bizzini B, Campbell T, Solanki R, Butler, R, Smith, J, Davidson, CM, Laurrieu D, Brand AH, Livesey FJ
biorxiv
Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal dementia neurons and extends lifespan in an in vivo Drosophila tauopathy model
Paonessa, F, Delarue Bizzini B, Campbell T, Solanki R, Butler, R, Smith, J, Davidson, CM, Laurrieu D, Brand AH, Livesey FJ
biorxiv

2024

Paonessa, F, Delarue Bizzini B, Campbell T, Solanki R, Butler, R, Smith, J, Davidson, CM, Laurrieu D, Brand AH, Livesey FJ
biorxiv
Lim K, APA Donovan, Tang W, Sun D, He P, Pett JP, Teichmann SA, Marioni JC, Meyer KB, Brand AH, Rawlins EL
Cell Stem Cell
Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease
Lim K, APA Donovan, Tang W, Sun D, He P, Pett JP, Teichmann SA, Marioni JC, Meyer KB, Brand AH, Rawlins EL
Cell Stem Cell

2023

Lim K, APA Donovan, Tang W, Sun D, He P, Pett JP, Teichmann SA, Marioni JC, Meyer KB, Brand AH, Rawlins EL
Cell Stem Cell
Tang JLY, Krautz R, Llorà-Batlle O, Hakes AE, Fox PM, Brand AH
STAR Protocols
In vivo, genome-wide profiling of endogenously tagged chromatin-binding proteins with spatial and temporal resolution using NanoDam in Drosophila
Tang JLY, Krautz R, Llorà-Batlle O, Hakes AE, Fox PM, Brand AH
STAR Protocols

2022

Tang JLY, Krautz R, Llorà-Batlle O, Hakes AE, Fox PM, Brand AH
STAR Protocols
Sun D, Llora-Batlle O, van den Ameele J, Thomas JC, He P, Lim K, Tang W, Xu C, Meyer KB, Teichmann SA, Marioni JC, Jackson SP, Brand AH, Rawlins EL
The EMBO Journal
SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling
Sun D, Llora-Batlle O, van den Ameele J, Thomas JC, He P, Lim K, Tang W, Xu C, Meyer KB, Teichmann SA, Marioni JC, Jackson SP, Brand AH, Rawlins EL
The EMBO Journal

2022

Sun D, Llora-Batlle O, van den Ameele J, Thomas JC, He P, Lim K, Tang W, Xu C, Meyer KB, Teichmann SA, Marioni JC, Jackson SP, Brand AH, Rawlins EL
The EMBO Journal
Fox PM, Tang JLY, Brand AH
Development
The Drosophila homologue of CTIP1 (Bcl11a) and CTIP2 (Bcl11b) regulates neural stem cell temporal patterning
Fox PM, Tang JLY, Brand AH
Development

2022

Fox PM, Tang JLY, Brand AH
Development
Tang JLY, Hakes AE, Krautz R, Suzuki T, Contreras EG, Fox PM, Brand AH
Developmental Cell
NanoDam identifies Homeobrain (ARX) and Scarecrow (NKX2.1) as conserved temporal factors in the Drosophila central brain and visual system
Tang JLY, Hakes AE, Krautz R, Suzuki T, Contreras EG, Fox PM, Brand AH
Developmental Cell

2022

Tang JLY, Hakes AE, Krautz R, Suzuki T, Contreras EG, Fox PM, Brand AH
Developmental Cell
van den Ameele J, Krautz R, Cheetham SW, Donovan APA, Llorà-Batlle O, Yakob R, Brand AH
Nature Communications
Reduced chromatin accessibility correlates with resistance to Notch activation
van den Ameele J, Krautz R, Cheetham SW, Donovan APA, Llorà-Batlle O, Yakob R, Brand AH
Nature Communications

2022

van den Ameele J, Krautz R, Cheetham SW, Donovan APA, Llorà-Batlle O, Yakob R, Brand AH
Nature Communications
Sênos Demarco R, Stack BJ., Tang AM, Voog J, Sandall SL, Southall TD, Brand AH, Jones DL
Cell Reports
Escargot controls somatic stem cell maintenance through the attenuation of the insulin receptor pathway in Drosophila
Sênos Demarco R, Stack BJ., Tang AM, Voog J, Sandall SL, Southall TD, Brand AH, Jones DL
Cell Reports

2021

Sênos Demarco R, Stack BJ., Tang AM, Voog J, Sandall SL, Southall TD, Brand AH, Jones DL
Cell Reports
Wade AA, van den Ameele J, Cheetham SW, Yakob R, Brand AH, Nord AS
In vivo targeted DamID identifies CHD8 genomic targets in fetal mouse brain
Wade AA, van den Ameele J, Cheetham SW, Yakob R, Brand AH, Nord AS

2021

Wade AA, van den Ameele J, Cheetham SW, Yakob R, Brand AH, Nord AS
Agrawal N, Lawler K, Davidson CM, Keogh JM, Legg R, INTERVAL, Barroso I, Farooqi IS , Brand AH
PLOS Biology
Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila
Agrawal N, Lawler K, Davidson CM, Keogh JM, Legg R, INTERVAL, Barroso I, Farooqi IS , Brand AH
PLOS Biology

2021

News coverage: EurekAlert!, MedicalResearch.com

Agrawal N, Lawler K, Davidson CM, Keogh JM, Legg R, INTERVAL, Barroso I, Farooqi IS , Brand AH
PLOS Biology
Contreras EG, Glavic A, Brand AH, Sierralta JA
The Journal of Neuroscience
The Serine Protease Homolog, Scarface, Is Sensitive to Nutrient Availability and Modulates the Development of the Drosophila Blood–Brain Barrier
Contreras EG, Glavic A, Brand AH, Sierralta JA
The Journal of Neuroscience

2021

Contreras EG, Glavic A, Brand AH, Sierralta JA
The Journal of Neuroscience
Díaz-Torres A, Rosales-Nieves AE, Pearson JR, Mateos C S-C, Marín-Menguiano M, Marshall OJ, Brand AH, González-Reyes A
Current Biology
Stem cell niche organization in the Drosophila ovary requires the ECM component Perlecan
Díaz-Torres A, Rosales-Nieves AE, Pearson JR, Mateos C S-C, Marín-Menguiano M, Marshall OJ, Brand AH, González-Reyes A
Current Biology

2021

Díaz-Torres A, Rosales-Nieves AE, Pearson JR, Mateos C S-C, Marín-Menguiano M, Marshall OJ, Brand AH, González-Reyes A
Current Biology
Cheetham SW and Brand AH
Methods in Molecular Biology
Mapping RNA-chromatin interactions in vivo with RNA-DamID.
Cheetham SW and Brand AH
Methods in Molecular Biology

2020

Cheetham SW and Brand AH
Methods in Molecular Biology
Hakes AE and Brand AH
eLife
Tailless/TLX reverts intermediate neural progenitors to stem cells driving tumourigenesis via repression of asense/ASCL1
Hakes AE and Brand AH
eLife

2020

Hakes AE and Brand AH
eLife
Otsuki L and Brand AH
Trends in Neurosciences
Quiescent Neural Stem Cells for Brain Repair and Regeneration: Lessons from Model Systems
Otsuki L and Brand AH
Trends in Neurosciences

2020

Otsuki L and Brand AH
Trends in Neurosciences
Aloia L, McKie MA, Vernaz G, Cordero-Espinoza L, Aleksieva N, van den Ameele J, Antonica F, Font-Cunill B, Raven A, Cigliano R A, Belenguer G, Mort RL, Brand AH, Zernicka-Goetz M, Forbes SJ, Miska EA and Huch M
Nature Cell Biology
Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration
Aloia L, McKie MA, Vernaz G, Cordero-Espinoza L, Aleksieva N, van den Ameele J, Antonica F, Font-Cunill B, Raven A, Cigliano R A, Belenguer G, Mort RL, Brand AH, Zernicka-Goetz M, Forbes SJ, Miska EA and Huch M
Nature Cell Biology

2019

Aloia L, McKie MA, Vernaz G, Cordero-Espinoza L, Aleksieva N, van den Ameele J, Antonica F, Font-Cunill B, Raven A, Cigliano R A, Belenguer G, Mort RL, Brand AH, Zernicka-Goetz M, Forbes SJ, Miska EA and Huch M
Nature Cell Biology
van den Ameele J and Brand AH
eLife
Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation
van den Ameele J and Brand AH
eLife

2019

van den Ameele J and Brand AH
eLife
Hakes AE and Brand AH
Current Opinion in Cell Biology
Neural stem cell dynamics: the development of brain tumours
Hakes AE and Brand AH
Current Opinion in Cell Biology

2019

PDF

Hakes AE and Brand AH
Current Opinion in Cell Biology
Gervais L, van den Beek M, Josserand M, Salle J, Stefanutti M, Perdigoto CN, Skorski P, Mazouni K, Marshall OM, Brand AH, Schweisguth F and Bardin AJ
Developmental Cell
Stem Cell Proliferation Is Kept in Check by the Chromatin Regulators Kismet/CHD7/CHD8 and Trr/MLL3/4
Gervais L, van den Beek M, Josserand M, Salle J, Stefanutti M, Perdigoto CN, Skorski P, Mazouni K, Marshall OM, Brand AH, Schweisguth F and Bardin AJ
Developmental Cell

2019

Gervais L, van den Beek M, Josserand M, Salle J, Stefanutti M, Perdigoto CN, Skorski P, Mazouni K, Marshall OM, Brand AH, Schweisguth F and Bardin AJ
Developmental Cell
Otsuki L and Brand AH
Developmental Cell
Dorsal-Ventral Differences in Neural Stem Cell Quiescence Are Induced by p57KIP2/Dacapo
Otsuki L and Brand AH
Developmental Cell

2019

News coverage: Business Weekly (page 30)

Otsuki L and Brand AH
Developmental Cell
van den Ameele J, Krautz R and Brand AH
Current Opinion in Neurobiology
TaDa! Analysing cell type-specific chromatin in vivo with Targeted DamID
van den Ameele J, Krautz R and Brand AH
Current Opinion in Neurobiology

2019

PDF

van den Ameele J, Krautz R and Brand AH
Current Opinion in Neurobiology
Jörg DJ, Caygill EE, Hakes AE, Contreras EG, Brand AH and Simons BD
eLife
The proneural wave in the Drosophila optic lobe is driven by an excitable reaction-diffusion mechanism
Jörg DJ, Caygill EE, Hakes AE, Contreras EG, Brand AH and Simons BD
eLife

2019

Jörg DJ, Caygill EE, Hakes AE, Contreras EG, Brand AH and Simons BD
eLife
Contreras EG, Egger B, Gold KS and Brand AH
Neural Development
Dynamic Notch signalling regulates neural stem cell state progression in the Drosophila optic lobe
Contreras EG, Egger B, Gold KS and Brand AH
Neural Development

2018

Contreras EG, Egger B, Gold KS and Brand AH
Neural Development
Doupé DP, Marshall OJ, Dayton H, Brand AH and Perrimon N
Proceedings of the National Academy of Sciences
Drosophila intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals
Doupé DP, Marshall OJ, Dayton H, Brand AH and Perrimon N
Proceedings of the National Academy of Sciences

2018

Doupé DP, Marshall OJ, Dayton H, Brand AH and Perrimon N
Proceedings of the National Academy of Sciences
Hakes AE, Otsuki L, Brand AH
Development
A newly discovered neural stem cell population is generated by the optic lobe neuroepithelium during embryogenesis in Drosophila melanogaster
Hakes AE, Otsuki L, Brand AH
Development

2018

Hakes AE, Otsuki L, Brand AH
Development
Contreras EG, Palominos T, Glavic Á, Brand AH, Sierralta J and Oliva C
Scientific Reports
The transcription factor SoxD controls neuronal guidance in the Drosophila visual system
Contreras EG, Palominos T, Glavic Á, Brand AH, Sierralta J and Oliva C
Scientific Reports

2018

Contreras EG, Palominos T, Glavic Á, Brand AH, Sierralta J and Oliva C
Scientific Reports

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